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is combined with Selegiline. Approved Atomoxetine Selegiline may increase the central neurotoxic activities of Atomoxetine. Approved, Investigational Propofol The risk or severity of adverse effects can be increased when Propofol is combined with Selegiline. Approved, Investigational Dihydrocodeine The risk or severity of adverse effects can be increased when Dihydrocodeine is combined with Selegiline. Approved, Investigational Betaxolol Selegiline may increase the hypotensive activities of Betaxolol. Approved, Investigational Loxapine The risk or severity of adverse effects can be increased when Selegiline is combined with Loxapine. Investigational Theophylline The metabolism of Selegiline can be decreased when combined with Theophylline. Since the mechanisms of these reactions are not fully understood, it seems prudent, in general, to avoid this combination of Selegiline and tricyclic antidepressants as well as Selegiline and selective serotonin reuptake inhibitors.

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Gene Name CYP2C19 Uniprot ID P33261 Uniprot Name Cytochrome P450 2C19 Molecular Weight 55930.545 Da References Preissner S, Kroll K, Dunkel M, Senger C, Goldsobel G, Kuzman D, Guenther S, Winnenburg R, Schroeder M, Preissner R: SuperCYP: a comprehensive database on Cytochrome P450 enzymes including. Approved Dapiprazole The risk or severity of adverse effects can be increased when Selegiline is combined with Dapiprazole. Approved Iloperidone The risk or severity of adverse effects can be increased when Selegiline is combined with Iloperidone. Illicit, Investigational, Vet Approved Cariprazine The metabolism of Cariprazine can be decreased when combined with Selegiline. Six years later: too risky in Parkinson's disease. Approved, Investigational Caroxazone Selegiline may increase the hypertensive activities of Caroxazone. PubMed:7995016 Deleu D, Northway MG, Hanssens Y: Clinical pharmacokinetic and pharmacodynamic properties of drugs used in the treatment of Parkinson's disease. Approved Esomeprazole The metabolism of Selegiline can be decreased when combined with Esomeprazole. Approved, Investigational Metyrosine Selegiline may increase the hypotensive activities of Metyrosine. Approved, Investigational Bosutinib The serum concentration of Bosutinib can be increased when it is combined with Selegiline. Approved, Investigational Procaterol The risk or severity of adverse effects can be increased when Selegiline is combined with Procaterol.

Approved Pinacidil Selegiline may increase the hypotensive activities of Pinacidil. Approved, Investigational Dexmedetomidine The risk or severity of adverse effects can be increased when Selegiline is combined with Dexmedetomidine. Approved, Investigational Tapentadol The risk or severity of adverse effects can be increased when Tapentadol is combined with Selegiline. Approved, Investigational Aripiprazole Aripiprazole may increase the hypotensive activities of Selegiline. Approved Iprindole Selegiline may increase the serotonergic activities of Iprindole.

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