thrombolytic agent (streptokinase or urokinase) may be used, after allowing the effects of prior anticoagulation to diminish. Intravenous1 to 2 minutes. Zehnter E, Pollok M, Ziegenhagen D,. With high or multiple doses or prolonged administration of fentanyl or sufentanil, the duration of action is prolonged because substantial plasma concentrations of these agents may be maintained during their clearance from tissue storage sites (although accumulation of sufentanil is less than that of fentanyl).
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Mechanism of action/Effect: Low to moderate doses of fentanyl and its derivatives produce analgesia. 01 Anemia in zidovudine-treated HIV-infected children Children ages eight months to 17 years: Doses of 50 to 400 Units per kg of body weight given intravenously or subcutaneously two to three times a week have been reported. Pavlin D, Coda B, Shen D,. The pharmacokinetics of alfentanil (R39209 a new opioid analgesic. However, administration of 500 Units per kg of body weight to female rats caused decreases in weight gain, delays in the appearance of abdominal hair, delayed purplle coupons 100 off eyelid opening, delayed ossification, and decreases in the number of caudal vertebrae in first-generation fetuses. Like other opioid analgesics, fentanyl derivatives may cause physical dependence following prolonged use. Dialyzer urea and creatinine clearances not significantly changed in r-HuEPO treated maintenance hemodialysis (MD) patients abstract. Abnormal eye movements (i.e., disconjugate gaze ) have also been reported during induction with alfentanil. Zachee P, Staal GEJ, Rijksen G,. Once-weekly subcutaneous administration of the entire week's dosage requirement may be sufficient to maintain some patients at the desired hematocrit range. Anesth Analg 1986; 65: 999-1003.